First to secede, last to arrive in the 21st century. From Kos:

57% of South Carolina Republicans said they do not believe in evolution, while 32% say they do. Just 25% believe global warming is real.

Kos gets that from the most recent poll (.pdf) of South Carolina Republicans by Public Policy Polling.

Former Congressman James L. Petigru’s famous remark in 1860 holds true to this day:

“South Carolina is too small for a republic and too large for an insane asylum.”

I lived in Charleston for nearly two years back in the Fifties; fortunately I was way too young to be infected with the insanity.